This was my first time through the game, and I did it with good karma. I decided to follow that lead and allow the ghouls and humans to co-exist. Afterall, Gob does it just fine. I met a man named Crowely about 20 minutes after I'd finished Tenpenny Tower. When the message showed that Tenpenny was dead...I was horrified that I could let that happen... I went back to investigate and met with Roy... after the conversation I had with him I was crushed that I came into a well established community and caused their deaths. I blasted Roy in the head with Crowley's sniper rifle. Even so, I'm still upset.